- Beth Israel Lahey Health (Boston, MA)
- …or equivalent, preferably with strong research experience in DNA cloning, transfection, protein expression and other molecular biology techniques. Experience in ... mouse handling is desirable, but not required. Applicants with good communication skills (oral and written) are particularly encouraged to apply. Interested applicants should submit a CV, and contact details for 3 referees to ###@bidmc.harvard.edu **Job… more
- Takeda Pharmaceuticals (Boston, MA)
- …execute independent analyses using proprietary tumor datasets. They will integrate gene expression , protein abundance, and genetic mutation data to support ... to race, color, religion, sex, sexual orientation, gender identity, gender expression , parental status, national origin, age, disability, citizenship status, genetic… more
- Lilly (Boston, MA)
- …drug development. This position requires deep expertise in antibody engineering, protein design, and immunology, combined with advanced machine learning capabilities ... models that simultaneously optimize for multiple developability criteria including expression yield, solubility, viscosity, and post-translational modifications, crucial for… more
- Takeda Pharmaceuticals (Boston, MA)
- …multimodal architectures that integrate diverse data types-omics, biomedical imaging, protein 3D structures, and molecular representations. This role requires deep ... molecular datasets. + Fine-tune and adapt pre-trained foundation models ( protein language models, chemical LLMs, vision transformers) for Takeda-specific… more
- Takeda Pharmaceuticals (Boston, MA)
- …optimization on active pipeline projects. You will work closely with protein engineers, computational scientists, and experimental teams to deliver predictive models ... into internal workflows. + Innovate, develop, and apply predictive models for protein design and developability engineering, utilizing large-scale NGS, in vitro, in… more
- Dana-Farber Cancer Institute (Boston, MA)
- …multispecific T cell engagers, etc. + Design, produce and optimize the expression and _in vitro_ function of logic-gated and/or multispecific CARs and antibodies. ... and yeast display strategies, affinity maturation approaches, etc.); + antibody expression and characterization technologies including but not limited to purity and… more
- Sanofi Group (Cambridge, MA)
- …enable scientists to make faster, more informed decisions in antibody discovery, protein engineering, and biologics optimization. You will own the product roadmap ... required with significant industry experience in computational biology (antibody discovery, protein design, large molecules or related topic). MS or PhD preferred.… more
- Takeda Pharmaceuticals (Boston, MA)
- …AI/ML methodologies for de novo antibody design and discovery, including fine-tuning protein language models and generative protein design. + Develop, implement, ... and foundational models. + Innovate, develop, and apply predictive models for protein design and developability engineering, utilizing large-scale NGS, in vitro, in… more
- Takeda Pharmaceuticals (Boston, MA)
- …the development and deployment of foundational models for antibody and protein sequence, structure, and function prediction. + Drive integration of physics-based ... one relevant area, such as: + Machine learning or deep learning + Protein or biotherapeutic design + Structural modeling or computational biophysics + Strong… more
- Sanofi Group (Framingham, MA)
- …unit operations such as centrifugation, viral inactivation, freezing/thawing, and protein stability. Support next generation process development, control strategy ... supplier + Process knowledge across multiple modalities (eg mAbs, small protein and peptide, bioconjugates, nucleotides, Gene/cell therapy, organic chemistry etc.) +… more