- AbbVie (Worcester, MA)
- …knowledge to carry out the job functions. + Strong understanding of protein biochemistry and analytical method development principles. + Experience in developing and ... optimizing methods for charge variant analysis, including both icIEF and CEX techniques, with the ability to transfer these methods to a QC environment. + Proficiency in AKTA purification and fractionation to support comprehensive characterization workflows. +… more
- ThermoFisher Scientific (Boston, MA)
- …troubleshooting RNA LC-MS analysis + Sample testing for lipid raw materials, protein ligands, and LNP formulations + Present the findings to the GEnD ... team and the disease project team to inform decision making and next steps + Maintaining RNA LC-MS instrument and order reagents and supplies as needed + Maintaining/document records of all experiment including methods, experimental results, and report… more
- AbbVie (Cambridge, MA)
- …advanced computational modeling and AI/ML approaches to optimize therapeutic protein design, enhance production efficiency, and accelerate genetic medicine ... development. . Expertise in predictive modeling, quantitative data analysis, and novel method development leveraging multi-modal preclinical, clinical, and real-world data. . Experience with optimizing and fine-tuning foundation models, and applying LLM,… more
- Sanofi Group (Cambridge, MA)
- …and utilize numerous assays to investigate small molecule modulation of target protein activity. Overall, the student will master assay development and small ... molecule screening processes, such as assay optimization, protein quantification, automation and statistical data handling methods. This position will focus on… more
- Lilly (Boston, MA)
- …Summary** Lilly Small Molecule Discovery is seeking a **Computational Scientist ** to join our **Novel** **Platforms** **Fragment-based Discovery** team. We ... **Additional Preferences:** + Hands-on experience with biophysical assays for protein characterization, binding analysis and Molecular Dynamics (MD). + Experience… more