- Sanofi Group (Framingham, MA)
- …including cell culture bioreactor operations and analytical equipment utilization (eg, Raman spectroscopy). + Contribute to the development of soft sensors for ... Raman spectroscopy signal processing. + Participate in cell counting...+ Participate in cell counting and metabolite prediction using Raman model generation via Multivariate Data Analysis (MVDA). +… more
- Sanofi Group (Framingham, MA)
- …Familiarity with process modeling (mechanistic/hybrid modeling, chemometric modeling eg PAT Raman ) and control + Strong communication and collaboration skills across ... Gain understanding of bioprocesses (eg cell culture) 3) Gain exposure to PAT Raman and integration with Digital Twin 4) Practice written and oral communication… more
- Sanofi Group (Framingham, MA)
- …modeling for monitoring, testing and process control-** 70%: . Chemometric (NIR/ Raman ) modeling (MVDA and ML/AI techniques), state observer, Kalman filter, Advanced ... : . Process modeling ((mechanistic / hybrid modeling, chemometric modeling eg PAT Raman ) and control (APC, MPC) . Strong communication skills, written and verbal… more
- Sanofi Group (Framingham, MA)
- …automation and control systems (such as PLCs, SCADA, PI, SynTQ, RAMAN etc.) + Experience with systems/network/validation, preferable in the chemical, pharmaceutical, ... foods, or other process industries is preferred + Electrical, Electronic Engineer or Chemical Engineer + Experienced in establishment of safe practices in a lab environment. + Proficient working with computer programs/applications such as Windows, VBA, MS… more
- Sartorius (Marlborough, MA)
- …such as HPLC, Nanoparticle Tracking Analysis, Flow Cytometry, and Raman Analysis. + Physicochemical Characterization: Support characterization of loaded ... nanoparticles for size, polydispersity, and zeta potential using DLS, NTA, and other particle characterization tools. + Stability and Release Studies: Conduct in vitro stability testing and release profiling under different physiological conditions. + Process… more
- Takeda Pharmaceuticals (Cambridge, MA)
- …along with hands on experience in multiple analytical techniques (DSC, TGA, HPLC, XRPD, Raman , PAT tools etc) and proven ability to work in a lab setting. Working ... knowledge of modalities outside of traditional small molecule (Oligonucleotides, Protacs) and in silico predictive tools/modeling highly valued **TRAVEL REQUIREMENTS:** + May require approximately 5-10% travel. **Takeda Compensation and Benefits Summary** We… more
- Sanofi Group (Framingham, MA)
- …processes. **Preferred Qualifications:** + Exposure to process monitoring & control concepts, PAT, RAMAN , NIR, SIMCA is a plus. + Exposure to heat transfer and ... thermodynamics concepts & modeling tools is a plus. + Exposure to statistical analysis concepts is a plus. + Familiarity with bioprocesses or pharmaceutical unit operations. + Experience working with data visualization tools or dashboards. + Familiarity with… more
- Sanofi Group (Waltham, MA)
- …on developing chemometric models using process analytical technologies (PAT) such as Raman and FTIR and integrating these with first principle and machine learning ... (ML) models for various units, including In Vitro Transcription (IVT) and T-mixing in drug substance and product process development. The candidate will have the opportunity to learn about mRNA technology and unit operations, and to demonstrate the benefits of… more