- Gilead Sciences, Inc. (Foster City, CA)
- …primary responsibility of this position is to lead biotransformation activities in the Drug Metabolism Department and in collaboration with the Clinical group. ... and in vivo to understand metabolic pathways to support drug discovery and development. More broadly, the scientist...for candidate compounds for a full understanding of their drug metabolism and pharmacokinetic (PK) behavior. This… more
- Gilead Sciences, Inc. (Foster City, CA)
- …and excretion data for these compounds for a full understanding of their drug metabolism and pharmacokinetic (PK) behavior. This will include representation of ... quantitative roles of enzymes in the disposition of those drug candidates (metabolic phenotyping). More broadly, the scientist...metabolic profiles of those compounds. + Serve as a drug metabolism and enzyme kinetics subject matter… more
- Merck (South San Francisco, CA)
- …interact with toxicology study directors, project representatives, bioanalytical scientists, drug metabolism and translational modeling representatives, and ... modeling (NCA analysis, nonparametric superposition, and compartmental PK modeling), and drug metabolism is required with demonstrated hands-on proficiency with… more
- Merck (South San Francisco, CA)
- …internal and external clinical study support staff and scientists (including discovery research , biostatistics, drug metabolism , modeling and simulation, ... Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism /Modeling & Simulation, Regulatory Affairs, and… more
- GAP Solutions Inc (Sacramento, CA)
- …ligands to image HIV viral reservoirs. These experiments will be performed by the Scientist , other INSS lab members, and contract research organizations. The ... to develop structure activity relationships (SAR) and improve compound activity. + Research and refine drug formulation protocols. + Analyze pharmacokinetic and… more
- AbbVie (South San Francisco, CA)
- …calculation of therapeutic index + Effectively communicate on strategies related to drug metabolism and pharmacokinetics (DMPK) and translational modeling and ... from Discovery into Development. AbbVie is a global organization with US research sites in Boston (Cambridge and Worcester, MA), Chicago (North Chicago, IL),… more
- Amgen (South San Francisco, CA)
- …you'll help make a lasting impact on the lives of patients as we research , manufacture, and deliver innovative medicines to help people live longer, fuller happier ... small molecule (SM) programs. You will characterize the absorption, distribution, metabolism , excretion (ADME) and pharmacokinetic (PK) properties of SM therapeutic … more
- Merck (South San Francisco, CA)
- …to revolutionize drug discovery and development? The Pharmacokinetics, Dynamics, Metabolism , and Bioanalytics (PDMB) department of Research Laboratories is ... AI/ML to support efforts in transforming the way PDMB leads the assessment of drug candidates. The successful candidate will join a dynamic Data Science team focused… more
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