- Lilly (Boston, MA)
- …optimizing and improving current methods for the characterization of raw materials, RNA drug substances, and LNP products and programs at various development stages. ... Additionally, the role includes testing non-GMP samples to support development studies such as comparability assessments, process development, stability, product, and process characterization. The position is part of a Technical Operations team that partners… more
- Massachusetts Institute of Technology (Cambridge, MA)
- …candidate will perform independent research to support solid-phase DNA & RNA synthesis using an automated nucleic acid synthesizer; nucleic acid conjugation; ... and purification. They will conduct quantitative nucleic acid analyses using HPLC, mass spectrometry, PCR, and electrophoresis. They will also be responsible for ordering lab supplies and reagents; and coordinating lab operations, safety compliance, protocol… more
- Danaher Corporation (Lexington, MA)
- …(eg Perl, Python, Java) + Hands-on experience with NGS applications ( RNA -seq, DNA-seq, etc.) and data processing (read alignment, quantification, quality assessment, ... etc.) + Experience with statistical analysis and interpretation with NGS or other 'omics datasets + Some familiarity with SQL and relational databases (eg Oracle) is a plus + Highly motivated self-starter + Must be able to work independently, while… more
- Lilly (Boston, MA)
- …novel gene editing products. The ideal candidate will have experience with RNA process development, tech transfer, and GMP manufacturing. In this highly ... collaborative role, you will help facilitate drug product tech transfer efforts and drive successful clinical manufacturing by external vendors. + Drive technical readiness and on-site support for manufactures of mRNA and gRNA across early-stage and late-stage… more
- Astellas Pharma (Cambridge, MA)
- …to inform decisions and development strategy + Broad technical experience in DNA, RNA , and protein-based biomarker assays (eg PCR, NGS, ELISA/MSD, IHC, IF, Mass ... spectrometry) + Experience in fit-for-purpose biomarker assay qualification/validation + An innovative mindset with track record of incorporating new technologies in translational and biomarker research + Strong communication skills (oral, written, and… more
- Lilly (Boston, MA)
- …+ Knowledge of emerging modalities including cell & gene therapy, RNA -based medicines + Strong analytical and problem-solving skills + Experience working ... with biotechs/emerging companies and/or early-stage development programs where speed to clinic is a critical success factor + Demonstrated ability to operate effectively in fast-paced environments where rapid decision-making and pragmatic problem-solving are… more
- Beth Israel Lahey Health (Boston, MA)
- …in Alzheimer's disease, the biology of resilience to disease, and precision RNA medicine. **Job Description:** **Essential Responsibilities (but not limited to):** + ... Serves as the administrative resource and liaison for the program, interacting with all levels of personnel, both internal and external. + Is knowledgeable in all aspects of assigned research trials to be able to evaluate questions and problems. + Ensures that… more
- AbbVie (Cambridge, MA)
- …+ Fluent in R and/or Python + Fluent in single-cell RNA -seq analysis + Excellent organizational, communication, collaboration, and interpersonal skills Preferred ... Qualifications + Expertise in immunology is a plus + Experience with image analysis is a plus + Experience with nextflow and GitHub Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements… more
- Lilly (Boston, MA)
- …storage (eg S3) + Experience working with additional data formats, including RNA -seq, metabolomic, and proteomic data + Experience with protein language models ... and/or sequence language models + Experience working with clinical data + Experience working with electronic health record data + Knowledge of AdAM and OMOP formats + Strongly team-oriented with a customer focused design thinking approach + Knowledge of drug… more
- Bristol Myers Squibb (Cambridge, MA)
- …and integrating high-dimensional molecular datasets such as multi-omics ( RNA -seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN ), single cell (CITE-seq, scATAC-seq, ... perturb-seq) and spatial profiling (Visium, GeoMx, CosMX ) + Experience implementing and/or developing statistical methodologies and machine learning algorithms applied to the biological problems + Background in Neuroscience, especially in neuro-degenerative… more