- Edwards Lifesciences (Irvine, CA)
- …for new or modified devices and/or processes) and lead in vitro and in vivo biocompatibility studies for new and in-process products including in vitro testing (eg, ... cytotoxicity, genotoxicity and hemocompatibility endpoints) and in vivo testing (eg, systemic toxicity, intracutaneous reactivity, implantation and sensitization… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …Ph.D. in biomedical sciences. The project involves both in vitro and in vivo experimentation at the intersection of immunology, cell biology, molecular biology and ... standard cell biology techniques as well as murine in vivo models is required, as well as microscopy and...standard cell biology techniques as well as murine in vivo models is required, as well as microscopy and… more
- Amgen (South San Francisco, CA)
- …Leveraging specialized ADME/PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK/PD, or physiologically-based pharmacokinetic modeling (PBPK) to ... technical experience with the application of SM in vitro/in vivo ADME and pharmacokinetics fundamentals to drug discovery projects...PKDM scientists. + Expertise with in vitro ADME, in vivo ADME, PK/PD or PBPK + Experience in supporting… more
- Stanford University (Stanford, CA)
- …The goal of our lab is to use unbiased genomic methods and in vivo models to better understand the molecular and cellular changes that underlie tumor progression ... role of the tumor microenvironment, on cancer initiation, progression and metastasis in vivo . Our work is focused on uncovering general rules that govern tumor… more
- Gilead Sciences, Inc. (Santa Monica, CA)
- …bring deep technical expertise and leadership in Lentiviral Vector (LVV) production for ex- vivo and in- vivo applications, with a proven track record of advancing ... candidates from research through IND-enabling studies as well as commercialization. In addition, this individual will drive robustness, innovation and compliance across LVV process development workflows, and ensure viral safety strategies are aligned with… more
- Amgen (South San Francisco, CA)
- …in a life sciences discipline with research experience spanning in vivo experimentation and molecular or cellular biology **Preferred Qualifications:** + ... Demonstrated experience with in vivo experimentation, including mouse models relevant to human disease + Familiarity with omics-based approaches (eg, single cell and… more
- Stanford University (Stanford, CA)
- …care and study implementation, help research staff design and implement in vivo studies, train and oversee lab members on animal training, veterinary care, ... IACUC protocols with the PI * Assist in the design and implementation of in vivo studies * Complete reports as required for research studies * May perform tasks… more
- Gilead Sciences, Inc. (Foster City, CA)
- …delivery efficiency and cellular tropism. + Design and coordinate in vivo studies in collaboration withtherapeutic areas to assess biodistribution, pharmacodynamics, ... in vivostudies for LNP evaluation and optimization. + Familiarity with additional in- vivo delivery platforms would be advantageous + Proficiency in data analysis… more
- Kelly Services (San Diego, CA)
- …+ Analyze data to inform product selection decisions + Oversee in vitro and in vivo screening of gene therapy candidates in animal models + Assist in AAV vector ... (eg, qPCR/ddPCR, western blotting, ELISA) + Experience with in vitro and in vivo assay design for gene therapy testing + Preferred: Experience preparing CMC… more
- Merck (South San Francisco, CA)
- …team-specific PDMB workflow. + Design and execute in vitro and in vivo mechanistic and translational studies to evaluate the pharmacokinetic and metabolic properties ... Knowledge in novel and translatable in vitro cellular models and/or in vivo models + In-depth understanding of modeling principles. Hands-on experience with modeling… more