- Takeda Pharmaceuticals (Boston, MA)
- …worldwide. **Position Overview** We are seeking an innovative and dynamic AI/ML Sr. Scientist with a passion for leveraging AI/ML in antibody discovery and design to ... protein design and developability engineering, utilizing large-scale NGS, in vitro, in vivo and other proprietary in-house and external data sources. + Manage and… more
- Dana-Farber Cancer Institute (Boston, MA)
- We are currently seeking an experienced scientist , preferably with a background in hematology and/or oncology, who will, in close collaboration with the PI and Sr. ... spatial proteomics/transcriptomics, and single-cell genomic characterization, in vitro, and in vivo work. + Experience in project management or lab operations. +… more
- Takeda Pharmaceuticals (Boston, MA)
- …and selection data from antibody surface display + Deep overall understanding of in vivo and in vitro antibody discovery platforms + Minimum 2 years of industry ... experience in hands-on NGS data analysis (RNAseq /scRNAseq) utilizing custom workflows and pipelines. + Demonstrated ability to write, test, automate, and benchmark computational pipeline tools with a focus towards biologics discovery. + Experience with AI/ML… more
- AbbVie (Worcester, MA)
- …identification/optimization to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. + Leverage expertise to develop & ... implement research to gain a detailed mechanistic understanding of molecular pharmacology of therapeutic molecules. + Generate internal & external collaborations as necessary to further program goals. + Drive antibody discovery programs within a… more
- Takeda Pharmaceuticals (Boston, MA)
- …discovery group. **Accountabilities:** + Design, perform, and interpret in vitro and ex vivo studies to evaluate drug candidate mechanisms of action + Generate data ... packages supporting candidate selection and asset characterization, leveraging subject matter expertise, technical literature, and awareness of current industry standards. + Champion scientific integrity and rigor in data analysis, preparation, and… more
- Takeda Pharmaceuticals (Boston, MA)
- …+ Experienced in the design, development and implementation of in vitro/ex vivo cell based functional assays to study target-specific drug effects. + Knowledgeable ... and experienced in cell biology, Immunology and antibody characterization. + Experienced with cell based functional assay platforms including, but not limited to, on-cell binding, reporter assay, Alphalisa, MSD, flow cytometry, cell adhesion, cell migration,… more
- Pfizer (Cambridge, MA)
- **Use Your Power for Purpose** This Senior Principal Scientist position will be a strong scientific and leadership role within the Early Formulation Science and Drug ... of the larger Pharmaceutical Sciences division. **ROLE SUMMARY** This Senior Principal Scientist position will be a strong scientific leadership role within the… more
- Lilly (Boston, MA)
- …people around the world. We are looking for a highly motivated and creative scientist with a deep technical background in mRNA therapeutic technology to join the ... through close internal collaborations. + Coordinate formulation and in vivo studies for validation of mRNA activity in relevant...screening assays in primary cells. + Experience with in vivo study design in mouse models. + Experience with… more
- Dana-Farber Cancer Institute (Boston, MA)
- The Cancelas Lab seeks a Postdoctoral Scientist to study leukemogenesis and targeting in leukemia. The applicant should have a doctoral degree in Biology, Molecular ... viral transduction, gene editing, immunoblotting, cell culture, colony-formation assays, ex vivo and in vivo modeling of cancer, immunohistochemistry, flow… more
- Lilly (Boston, MA)
- …for people around the world. Our diverse ADME team is seeking a dedicated scientist with an interest in the discovery and clinical development of genetic medicines, ... of diverse data (eg, in silico, in vitro, in vivo ) to interpret complex data sets and to derive...ADME/DMPK characteristics **Lilly seeks a skilled ADME / DMPK scientist who will:** + Lead and innovate in a… more