- BioBridge Global (San Antonio, TX)
- …in vitro characterization of cell therapy products using protein and gene expression analysis. Demonstrate broad working knowledge of platforms and technologies ... processing techniques in mammalian cell expansion pertinent to cell and gene therapy. Hands-on experience with next-generation sequencing platform is a plus.… more
- Editas Medicine (Cambridge, MA)
- …allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing. We believe our people are at the core of everything we do, ... CMC focus health authority meetings. + Accountable for the management and delivery of all CMC regulatory milestones, including global investigational drug filings… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …and translation of nanoparticle chemistries. This work will ultimately result in the delivery and development of new applications for mRNA and other RNA-based drugs. ... The drugs may consist of vaccines, gene replacement therapies, mRNA-encoded antibodies, CRISPR gene ...The focus of the programs will be on extrahepatic delivery , and will therefore require both de-targeting the liver… more
- The Mount Sinai Health System (New York, NY)
- …and genetic characterization of cyclin-dependent protein kinases (CDKs) involved in regulating gene expression in human cells. Specifically, he/she will focus on the ... into how Cdk7 regulates the RNA polymerase II transcription cycle and coordinates gene expression with cell division. The candidate's findings will be reported in… more
- The Mount Sinai Health System (New York, NY)
- …a broad array of well-established techniques such as mouse genetics, CRISPR gene editing, culturing and differentiation of iPSCs and organoids, microdissection of ... RNA-seq, and single-cell sequencing technologies, and/or other specialized approaches to study gene regulation at the cellular and tissue level. Projects in our labs… more
- Lilly (Lebanon, IN)
- …LP-2, Lebanon, Indiana, will be a leadership development role, responsible for successful delivery of production areas and gene therapy facility startup. These ... cutting-edge facility for the manufacture of new modalities including Gene Therapy in Lebanon, Indiana. This facility will be...Lilly's most technically advanced manufacturing site focused on the delivery of the next wave of innovative products at… more
- ThermoFisher Scientific (Plainville, MA)
- …supply and offer the expertise and resources vital to help clients deliver innovative gene therapies. Placed in the forefront of our leading and cutting edge Cell ... and Gene Therapy business enabling clients to cure genetic, rare,...+ Resolve material shortages, which are caused by supplier delivery delays, non-conforming material or other problems, to satisfactory… more
- University of Pennsylvania (Philadelphia, PA)
- …in laboratory management, and lead multiple research projects related to cell and gene therapy, and contribute to the development and implementation of assays for ... samples, expertise in genetic engineering through viral or non-viral delivery methods, multi-color flow cytometry, general laboratory operations, and familiarity… more
- Catalent Pharma Solutions (Harmans, MD)
- …to drive the facility fit and technical transfer of mammalian, microbial, Gene and Cell Therapy and viral vector biologic processes, including the evaluation, ... preparation for commercialization. + Leads strategic alignment across Catalent Cell and Gene Therapy sites. + Lead the evaluation, remediation and optimization of… more
- Sandia National Laboratories (Livermore, CA)
- …in cell culture models. We are currently using various CRISPR systems to alter gene expression through genome editing, gene activation or mRNA targeting tools. ... mRNA targeting) + Develop cell reporter assays + Design viral vectors for in vivo delivery + Coordinate with cross-disciplinary team to move from in vitro to in vivo… more