- Amgen (Thousand Oaks, CA)
- …platforms **Cross-Functional Collaboration** : Partner closely with in vivo pharmacologists, protein biochemists, structural biologists, medicinal chemists, ... and/or related areas. + Deep technical expertise in signal transduction, metabolic regulation, and/or in vitro pharmacology. + Demonstrated creativity and scientific… more
- The County of Los Angeles (Los Angeles, CA)
- …and our communities by providing extraordinary care. DEFINITION: Performs advanced metabolic and advanced dynamic radioisotope scanning tests and associated wet ... Adapts new nuclear medicine procedures for routine use. + Performs metabolic tests including ferrokinetic, albumin turnovers calcium absorption, protein turnover,… more
- Mount Sinai Health System (New York, NY)
- …to residual cardiovascular disease risk. Using a combination of in vivo physiology, molecular biology, stable isotope tracer methodology and integrative multi-omics, ... we aim to define the critical metabolic pathways that underlie atherosclerotic plaque progression and vulnerability. We are currently focused on two integrated areas… more
- University of Colorado (Aurora, CO)
- …Associate** Key Responsibilities: + Conceive, plan, and direct in-vitro and in- vivo studies focused on trauma-induced inflammation and liver biology. + Maintain ... and immortalized cell cultures and oversee advanced cellular assays (eg, metabolic flux, CRISPR-based screens). + Conduct mouse procedures under IACUC protocols,… more
- Merck (South San Francisco, CA)
- …pharmacology. Therapeutic areas may include immunology and oncology, cardiovascular and metabolic disease, and ophthalmology. The Senior Scientist will be a member ... Ideal candidate is expected to independently plan and conduct in vitro/ex vivo studies, independently interpret data, clearly present data to teams, and integrate… more
- Amgen (South San Francisco, CA)
- …areas including Oncology, Inflammation, General Medicine, and Cardiovascular or Metabolic diseases The successful candidate will bring expertise in high-dimensional ... genomics analysis and surfaceome-based target discovery projects using in vitro and ex vivo models (cell lines, organoids, tissues). + Assist to develop and apply… more
- Dana-Farber Cancer Institute (Boston, MA)
- …and chemoproteomics studies + Help develop and apply biochemical, biophysical, and metabolic stability assays + Screen compounds; analyze and interpret data + Apply ... iterative design of optimized chemical probes suitable for cellular and in vivo pharmacological studies + Maintain accurate lab records and documentation +… more
- University of Pennsylvania (Philadelphia, PA)
- …oligodendrocytes, imaging and analysis of oligodendrocyte in vitro and in vivo using fluorescence, confocal, live cell microscopy, knowledge of cellular organellar ... Division of Child Neurology with basic neuroscientists, developmental pediatrics, metabolic medicine, psychiatry, cardiology, critical pediatric and neonatal medicine,… more
- Otsuka America Pharmaceutical Inc. (Boston, MA)
- …to a team of translational scientists developing primary human cell and ex vivo systems to support program hypotheses and biomarker discovery. + Support regulatory ... + Strong background in immunology and rheumatological disease; knowledge of nephrology or metabolic disease is a plus. + Proven track record in biomarker strategy… more
- Mount Sinai Health System (New York, NY)
- …non-coding RNAs, stable-isotope-labeling mass spectrometry, in vitro and in vivo imaging, live imaging of exosomes, microfluidics isolation, bionanotechnology, ... flow cytometry, histology of the heart, echocardiography, MTT assay to assess metabolic activity, Western blot, PCR, RNA sequencing and data analysis, exosomes… more
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