- Bristol Myers Squibb (Cambridge, MA)
- …PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK /PD, or physiologically based pharmacokinetic modeling (PBPK) to impact project ... (absorption, distribution, metabolism, and excretion), DDI (drug-drug interactions) and PK (pharmacokinetics) support for all pipeline assets throughout clinical… more
- BeOne Medicines (Emeryville, CA)
- …The Director of Biostatistics will provide strategic statistical leadership for pharmacokinetic ( PK ) and pharmacodynamic (PD) studies across all phases ... analysis, and timely support for global regulatory submissions. Deep expertise in PK modeling, including non-compartmental and population PK analysis, and… more
- Merck (West Point, PA)
- …The ideal candidate will have an in-depth understanding of ADME, as well as pharmacokinetic and PK /PD principles that impact the discovery and development of new ... modalities across therapeutic areas is desired. The candidate should be familiar with PK , PK /PD and PBPK modeling as tools to drive decision making. We are… more
- Gilead Sciences, Inc. (Foster City, CA)
- …of this Biologics DMPK Director position is to serve as an expert in the PK and PK /PD of biologics, representing the DMPK department by providing strategic and ... discovery and development as a subject matter expert for DMPK Biologics, providing PK or PK /PD expertise to the design of nonclinical PK , toxicology, or… more
- Merck (Rahway, NJ)
- …programming expertise with clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data, derived PK parameters). **Preferred ... high quality statistical programming analysis and reporting deliverables for global PK modeling and simulation stakeholders spanning all therapeutic areas. The… more
- Bayer (Whippany, NJ)
- …label. The CPL will develop and execute clinical pharmacology (CP), pharmacokinetic /pharmacodynamic ( PK /PD) plans and model-informed drug development strategies ... CP sub-team; + Design, execute, and coordinate the CP, PK /PD and MIDD strategies, aligning core CP studies with...America; + Lead the development of the clinical pharmacology ( PK , PD, biomarkers, bioanalytical) sections of early and late-stage… more
- Children's Hospital Los Angeles (Los Angeles, CA)
- …be responsible for supporting development and maintenance of population pharmacokinetic /dynamic analysis, simulation and dosing programs. The CHLA INSPIRE ... hollow fiber infection model (HFIM) to mimic human pharmacokinetics and pharmacodynamics ( PK -PD) in vitro to improve dosing strategies and select ideal combination… more
- Takeda Pharmaceuticals (Boston, MA)
- …is seeking a strong candidate to be a part of the Physiologically Based Pharmacokinetic (PBPK) modeling team for supporting drug-drug interaction (DDI) and PK ... distribution to inform drug-target coverage and safety margins, predicting absorption and PK , and evaluating the impact of drug-drug interactions + Predict PK… more
- AbbVie (North Chicago, IL)
- …clinical pharmacology, and other stakeholders, developing and executing QTAS and PK /PD strategies necessary to facilitate the advancement of our pipeline. ... selection, and candidate selection + Develop and drive the QTAS and PK /PD strategy for large molecule discovery, preclinical, and clinical development projects to… more
- Boehringer Ingelheim (Ridgefield, CT)
- …and implementing Clinical Pharmacology strategies (eg, assessment of pharmacokinetic /pharmacodynamic ( PK /PD), drug interaction, formulation development, dose ... selection decision, impact of renal/hepatic impairment, food effect on PK , QT prolongation and pediatric drug development). The Director, Clinical Pharmacology Lead… more