- Gilead Sciences, Inc. (Oceanside, CA)
- …workflows (HILIC-FLD, LC-MS, CE-LIF etc.), including sialic acid, NGNA, α‑Gal characterization and quantitation analysis. + Drive advanced structural elucidation of ... glycan occupancy, site-specific heterogeneity, and structural impacts on the protein backbone. + Integrate glycan structural information with functional outcomes… more
- University of North Carolina- Chapel Hill (Chapel Hill, NC)
- …broader research community in exploring novel drug targets. Key Responsibilities: - Protein Expression and Purification: Design and execute recombinant protein ... both prokaryotic and eukaryotic expression systems. - Biochemical and Biophysical Characterization : Develop and perform assays to identify and characterize … more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- …contribute to the identification of potential therapeutic antibodies, the in vitro characterization and selection process of lead molecules in the early antibody ... Scientist, a typical day might include:** + Designing and optimizing in-vitro protein or cell-based immunoassays, including but not limited to flow cytometry, high… more
- Mount Sinai Health System (New York, NY)
- …Comprehensive training in structural biology techniques such as cryo-EM and protein crystallization. + An opportunity to contribute to high-impact research projects ... structure research, completed within the last three years. + Proficiency in protein expression and purification in eukaryotic and prokaryotic systems. + Experience… more
- AbbVie (South San Francisco, CA)
- …& ADME Sciences (QTAS) team in South San Francisco supports the characterization , modeling the ADME (Absorption, Distribution, Metabolism, and Excretion) aspects of ... learning models for biologics sequence-to-property prediction, tapping into dynamic protein conformations through ensemble structures. Key responsibilities include: +… more
- Bristol Myers Squibb (Seattle, WA)
- …develop and execute LC-MS methods to support oligonucleotide process development and characterization , as well as the characterization of autologous and ... CE, SEC/AEX-MALS, preparative LC-MS-for sample quality control and the characterization of oligonucleotides and proteins. + Maintain and troubleshoot instrumentation… more
- AbbVie (San Francisco, CA)
- …The ideal candidate must possess expertise in high-throughput biologics screening and characterization methods (eg ELISA, FACS, BLI, SPR, etc.) and have a solid ... foundation in protein sciences and antibody discovery with a proven ability...guide therapeutic candidate selection recommendations. + Expert in biophysical characterization instrumentation and methodologies such as SEC, MS, HDX-MS,… more
- US Tech Solutions (Thousand Oaks, CA)
- …advanced laboratory execution (cell culture, reagent generation and characterization ) with technical leadership of process development, laboratory automation, ... and replenishment triggers. + Perform and support advanced reagent work: antibody/ protein purification and conjugation. + Translate research and experimental results… more
- Adecco US, Inc. (Framingham, MA)
- …methodologies used to generate recombinant CHO cell lines for protein biologics manufacturing. Responsibilities include designing next-generation vector topologies ... candidate biotherapeutics in mammalian cell systems + Perform molecular characterization using ddPCR, Sanger sequencing, restriction mapping, and related techniques… more
- AbbVie (South San Francisco, CA)
- …timelines and outcomes for cell line, mammalian cell culture, and protein therapeutic purification development. + Develop and perform molecular techniques for ... the engineering and characterization of CHO production cell lines. + Perform mammalian...cell lines. + Perform mammalian suspension cell culture and protein separation methodologies to develop robust processes as part… more
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