- NVIDIA (Santa Clara, CA)
- …(eg, PyG, cuEquivariance, e3nn) + Experience with modeling and validation of protein sequences and/or protein structures and related tools + Recognition ... biological and materials sciences, including AlphaFold3, BioEmu, GNoMe + Background with protein or small molecule or material simulation tools that use atomistic or… more
- University of Maryland, Baltimore (Baltimore, MD)
- …disorders, in particular dementias. Areas of expertise might include gene expression in either human blood or brain specimens using RNASeq, oligonucleotide ... arrays, or transgenic system approaches; proteomics and broad based protein analyses such as post-translational modification, eg, protein phosphorylation or… more
- Takeda Pharmaceuticals (Boston, MA)
- …AI/ML methodologies for de novo antibody design and discovery, including fine-tuning protein language models and generative protein design. + Develop, implement, ... and foundational models. + Innovate, develop, and apply predictive models for protein design and developability engineering, utilizing large-scale NGS, in vitro, in… more
- Gilead Sciences, Inc. (Foster City, CA)
- …guide interdisciplinary projects, with experts in oncology, immune-oncology, protein engineering, chemistry, translational medicine, biomarkers and clinical ... of cancer, _in vitro_ and _in vivo_ , with experience in biochemically analyzing protein (and protein -nucleic acid) complexes a plus. + Demonstrated success in… more
- University of Colorado (Boulder, CO)
- …mechanisms of the proteasome, a molecular machine essential for cellular protein degradation. A prospective Post-Doctoral Fellow will investigate mechanisms of ... signals, and evolutionarily conserved chaperones, including Gankyrin, a known onco- protein in humans. A prospective Post-Doctoral Associate will interrogate these… more
- University of Colorado (Boulder, CO)
- …mechanisms of the proteasome, a molecular machine essential for cellular protein degradation. We recently discovered mechanisms of "novel spatial quality control" ... new mechanism involves evolutionarily conserved chaperones, including Gankyrin, a known onco- protein in humans. A prospective Professional Research Assistant will be… more
- Takeda Pharmaceuticals (Boston, MA)
- …the development and deployment of foundational models for antibody and protein sequence, structure, and function prediction. + Drive integration of physics-based ... one relevant area, such as: + Machine learning or deep learning + Protein or biotherapeutic design + Structural modeling or computational biophysics + Strong… more
- Genentech (South San Francisco, CA)
- …**Who You Are:** * Ph D in Molecular Biology, Structural Biology, Biochemistry, Protein Chemistry or a related discipline. * One or more first author research ... publications in high quality journals in protein /antibody engineering or a related field. *...from rational design, through generation of mutants, to the expression , purification and characterization of mutant proteins * Creative… more
- Michigan State University (East Lansing, MI)
- …govern plant resilience. The project integrates bioinformatics, molecular genetics, protein structural prediction, and experimental validation to investigate their ... functional roles of prioritized candidate genes + Develop and apply protein turnover assays using fluorescent-tagged constructs and metabolite treatments +… more
- Mount Sinai Health System (New York, NY)
- …is available immediately. The Bernstein lab studies epigenetic regulation of gene expression and chromatin structure in cancer and development, with the long-term ... driven to study cancer epigenetics ideally with the following qualifications: - Protein biochemistry including protein purification, mass spectrometry sample prep… more