- Genentech (South San Francisco, CA)
- …within Development Sciences. The tPKPD department applies preclinical models (in silico, in vitro , or in vivo) to determine the pharmacokinetics (what the body does ... to the drug) and/or pharmacodynamics (what the drug does to the body) of therapeutics. The information obtained from such work is often used to help inform the selection of lead molecules, optimize dosing regimens, and understand the PK behavior of different… more
- Tufts Medicine (Boston, MA)
- …not promote excess vasodilation and hypotension. We employ a variety of in vitro , cell culture, and in vivo techniques, including signaling studies, cardiac myocyte ... culture, and invasive hemodynamic measurements. The laboratory anticipates performing single-cell measurements of cardiac myocyte con traction and calcium influx. We seek a highly motivated Postdoctoral Research Fellow, ideally with prior experience and/or a… more
- Merck (Rahway, NJ)
- …the necessary research work (Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology). ... The position will report directly to the Distinguished Scientist and Global Head, our Company's Research & Development Liaison and Discovery - Non-infectious Diseases. **Education:** + Required: DVM/VMD, as well as a PhD in experimental pharmacology **Required… more
- Eurofins US Network (Arvada, CO)
- …developing presence in highly specialised and molecular clinical diagnostic testing and in- vitro diagnostic products._ _In over 35 years, Eurofins has grown from one ... laboratory in Nantes, France to 61,000 staff across a decentralised and entrepreneurial network of ca. 900 laboratories in 61 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition,… more
- Merck (West Point, PA)
- …modalities. The Associate Principal Scientist will design and interpret in silico, in vitro , and in vivo analyses to support the discovery of therapeutics with the ... desired DMPK profile. They will assess DDI risk using static mechanistic and/or physiologically based pharmacokinetic (PBPK) models and guide clinical development teams on DDI strategy. They will author source reports and documents in support of regulatory… more
- Genentech (San Diego, CA)
- …for LNP-mediated delivery of nucleic acid payloads. + Co-lead screening efforts, in vitro and in vivo, working closely with molecular and in vivo pharmacology ... groups, to identify novel LNP formulations for optimal tissue/cell delivery. + Collaborate with diverse groups across the organization, including those representing cell therapy, vector engineering, pharmacology, translational biology, immuno-oncology, CMC,… more
- Avispa Technology (Pleasanton, CA)
- …Experience in digital PCR platforms is desirable. * Experience with developing In- vitro Diagnostic products is desirable. * Experience in implementing workflow on ... semiconductor based sensing devices or microfluidic devices is desirable. * Scripting/programming experience (Python, R, or equivalent) is a plus. * Translate complex scientific workflows into reliable, scalable system solutions. more
- Carnegie Mellon University (Pittsburgh, PA)
- …bioprinting systems, including 3D-ICE and light-pipe FRESH platforms. + Coordinate in vitro efficacy testing and in vivo safety and functionality studies in rodent ... and porcinemodels. + Collaborate with regulatory teams to support IND-enabling studies and documentation. + Mentor graduate students, postdocs, and junior staff across CMU and partner institutions, providing technical guidance, career development support, and… more
- Genentech (South San Francisco, CA)
- …field + Experience with in vivo cancer models (eg GEMM, xenograft) and in vitro cancer assays. + Experience with bulk and/or single-cell omics data analysis (eg bulk ... RNA-seq, ATAC-seq, ChIP-seq and single-cell RNA-seq/ATAC-seq) + Proficiency in R or Python is required + Demonstrated ability to drive at least one key research project, as evidenced by first-author publications in high-impact journals + Strong communication… more
- Eurofins US Network (San Jose, CA)
- …developing presence in highly specialized and molecular clinical diagnostic testing and in- vitro diagnostic products. In over 30 years, Eurofins has grown from one ... laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition,… more