- Merck & Co. (South San Francisco, CA)
- Job DescriptionWe are seeking an exceptional computational protein engineer to join the Discovery Biologics Protein Engineering department in South San Francisco ... to drive the advancement and application of computational antibody and protein designs and optimization in support of our biotherapeutic portfolio drug discovery… more
- Twist BioScience (South San Francisco, CA)
- Computational Scientist, AI/ML & Protein Design (Hybrid in South San Francisco, CA)Job DescriptionTwist is seeking a Computational Scientist to join our ... and data scientists to develop cutting-edge computational solutions for protein design, contributing to accelerating and scaling Twist Biopharma Solutions'… more
- Aequor (Thousand Oaks, CA)
- …8-5 Ideal candidate: BS in biochemistry, chemistry, biology, or a related protein or synthetic biotechnology sciences field or an equivalent level of ... and QC testing. BS in biochemistry, chemistry, biology, or a related protein or synthetic biotechnology sciences field or an equivalent level of biopharmaceutical… more
- Eisai, Inc (Exton, PA)
- …or in combination with other techniques, to test and characterize protein -based biopharmaceuticals. The person will author protocols; reports; author and revise ... or in combination with other techniques, to test and characterize protein -based biopharmaceuticals. The person will author protocols; reports; author and revise… more
- BioAgilytix (San Diego, CA)
- …and leadership experience overseeing regulated bioanalysis, tissue analysis, protein binding, CYP inhibition/induction, CYP phenotyping, and metabolite profiling/ID. ... and oversee the following study types: regulated bioanalysis, tissue analysis, protein binding, CYP inhibition, CYP induction, CYP phenotyping or metabolite… more
- Merck & Co. (Rahway, NJ)
- …technology platforms for quantitative and semi-quantitative determination of protein analyte using immunoassay principles (our Company, ForteBio, AlphaLISA, ... technologies including proteomics and the use of proteomic LC-MS for protein profile comparison.Knowledge of using statistics in data analysis and familiar… more
- Merck & Co. (South San Francisco, CA)
- …knowledge of the workflows required for the discovery and progression of protein therapeutics to developmentState of the art knowledge and experience in antibody ... and collaboration abilities Preferred Experience and Skills: Experience in protein therapeutics beyond traditional mAbs including alternative non-Ig scaffolds, bi-… more
- Merck & Co. (Rahway, NJ)
- …changing environment. - Preferred Experience and Skills:- Understanding of protein degradation mechanisms and link between analytical methodologies for analysis. ... of various Biologic modalities (eg, mAb, antibody-drug conjugate, fusion protein ). - Established scientific reputation supported by publications and external… more
- Merck & Co. (Boston, MA)
- …VAEs, flow models), and sequence/structure models (eg, transformers, GNNs, protein or RNA models)Familiarity with cheminformatics/biophysics toolkits (eg, RDKit), ... docking or molecular simulation, ADMET modeling, or DMPK-relevant endpointsPractical experience with experimental design, active learning, uncertainty quantification, or multi-objective optimizationSoftware engineering best practices (Git, testing,… more
- Merck & Co. (Rahway, NJ)
- …and managing CROs/CMOs is highly preferred.Familiarity with biocatalysis, protein engineering, biotherapeutics, and/or vaccines is a plus.Demonstrated ability ... to lead collaborative multi-disciplinary teams for successful outcomes.Demonstrated ability to coach and mentor other researchers.Excellent communication and organizational skills.Strong track record of peer-reviewed publications and research… more
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