- AbbVie (South San Francisco, CA)
- …will establish innovative translational modeling approaches, such as mechanistic PK / PD or systems modeling, across disease and therapeutic areas, as ... ADME Sciences (QTAS) group is searching for a Senior Scientist to provide mechanistic and translational modeling...and other stakeholders, to develop and execute QTAS and PK / PD strategies necessary to facilitate the advancement… more
- Amgen (South San Francisco, CA)
- … Translational and Clinical Pharmacology approaches - such as Pharmacokinetic / Pharmacodynamic ( PK / PD ) modeling, Mechanistic-Physiologically Based ... Pharmacokinetic (M-PBPK) modeling, Mechanistic-PBPK- Pharmacodynamic (M-PBPK- PD ) modeling, Quantitative Systems Pharmacology (QSP) modeling - integrated with… more
- AbbVie (Irvine, CA)
- …to contribute to optimizing translational sciences strategies. + Analysis of PK / PD data, both clinical and nonclinical, through the use of sophisticated ... modeling and simulation expert with matrix project teams. Specific responsibilities include: + Apply PK and PK / PD modeling/simulation to guide the design and… more
- Bristol Myers Squibb (Cambridge, MA)
- …as part of the lead selection process, utilizing strong foundational knowledge of building PK , PD , BioD and efficacy relationship in vivo and employ innovative ... ability to independently develop focused in vivo strategies and utilizing PK / PD /efficacy data to drive discovery, optimization, and characterization of… more
- US Tech Solutions (South San Francisco, CA)
- …development, optimization and implementation and routine LC/MS-based bioanalytical methods to support in vivo PK , TK, and PK / PD studies as well as in vitro ... + Prior industry experience in drug discovery/development is preferred. In-depth understanding of PK , TK and PK / PD studies and corresponding bioanalytical… more
- Genentech (South San Francisco, CA)
- …Pharm studies, as well as other M&S strategy/support such as population PK / PD models, disease models, statistical models, quantitative system pharmacology (QSP) ... Department at Genentech, Inc. is seeking Ph.D. level Senior Scientist , Principal Scientist , or Senior Principal ...at the right dose via the right route. Physiologically-based Pharmacokinetic (PBPK) modeling will be a key focus of… more
- Merck (South San Francisco, CA)
- …workflow. + Design and execute in vitro and in vivo mechanistic and translational studies to evaluate the pharmacokinetic and metabolic properties of therapeutic ... and other modalities, to influence drug design, lead selection, and drive PK / PD translations. Be accountable for providing timely and high-quality PDMB… more
- AbbVie (Worcester, MA)
- …a Senior Scientist include developing and executing bioanalytical strategies to support PK , PD , and TK studies using ligand binding assay platforms. This ... PhD with 0+ years experience + Previous experience conducting DMPK studies, PK / PD /TK bioanalysis on antibodies, bi/multi-specifics and/or ADCs, including data… more
- Regeneron Pharmaceuticals (Tarrytown, NY)
- …/ PD analyses such as but not limited to NCA, compartmental modeling, PopPK, translational modelling, disease modelling, Pop PK / PD , E-R analyses (or in ... in this role is responsible for the execution of PK , PD , and other types of quantitative...apply standardized scientific techniques to analyze in-vivo and in-vitro pharmacokinetic & pharmacodynamic studies. We need this… more
- J&J Family of Companies (Spring House, PA)
- …aspects of aggregate and participant level data, including patient screening/eligibility evaluation, PK / PD data, adverse events, efficacy, coding, and other data ... Plan and Medical Review Forms + May liaise with vendor laboratories, Translational Research lead, pharmacokinetic operations and/or biomarker operations to… more