• Merck & Co. (South San Francisco, CA)
    …Sciences (DPS) group based in South San Francisco, CA is seeking an Principal Scientist with small molecule and peptide experience.DPS is a multi-disciplinary ... the progression of clinical candidate selection including Safety Assessment, Process Research, Medicinal Chemistry , Analytical Chemistry , and Drug Metabolism… more
    HireLifeScience (12/03/25)
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  • Merck & Co. (Rahway, NJ)
    Job DescriptionThe Principal Scientist , Drug Discovery in our Research and Development Department will be responsible for identifying new molecular entities and ... a matrix structure to garner resources for the necessary research work ( Medicinal and Process Chemistry , in vitro Pharmacology, Pharmacokinetics, Disease Models,… more
    HireLifeScience (12/04/25)
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  • Merck & Co. (South San Francisco, CA)
    …milestones are met and risks are proactively addressed.Collaborate cross-functionally with medicinal chemistry , pharmacology, clinical, and regulatory teams to ... Job DescriptionWe are seeking an experienced scientist to join our team and drive innovation in respiratory medicine. The ideal candidate will bring deep expertise… more
    HireLifeScience (12/04/25)
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  • Merck & Co. (Rahway, NJ)
    …- Under the guidance of dCMC Regulatory-Authoring Leadership, the Associate Principal Scientist , Regulatory Authoring Business Owner, will-optimize regulatory ... Transformation, Drug Development, Key Performance Indicators (KPI), Measurement Analysis, Medicinal Chemistry , Operating Models, Operational Excellence, Portfolio,… more
    HireLifeScience (11/27/25)
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  • Principal Scientist I / II,…

    Schrodinger (Cambridge, MA)
    We're looking to hire a ** Principal Scientist in Medicinal Chemistry ** to join us in our mission to discover and develop drugs that improve human health ... qualifications. **Who will love this job:** + A passionate scientist with a robust background in structure-based drug design...a medicinal chemist + Support and execute medicinal chemistry strategies to deliver high quality… more
    Schrodinger (10/11/25)
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  • Senior Principal Scientist

    Schrodinger (NY)
    We're looking to hire a **Senior Principal Scientist ** or **Director of Medicinal Chemistry ** to join us in our mission to discover and develop drugs ... discovery programs in effective collaboration with cross-functional teams + Execute medicinal chemistry strategies to deliver high-quality clinical candidates +… more
    Schrodinger (10/11/25)
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  • Senior Principal Scientist

    Bristol Myers Squibb (San Diego, CA)
    …are seeking a talented and highly motivated individual with a strong background in medicinal chemistry to join our Discovery and Development Sciences (D&DS) team ... The individual will apply modern drug design principles to solve medicinal chemistry problems relevant to the Protein Homeostasis Thematic Research Center… more
    Bristol Myers Squibb (12/06/25)
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  • Principal Scientist , Computational…

    Frontier Medicines (Boston, MA)
    …Medicines is seeking a highly motivated individual to fill the position of Principal Scientist , Computational Chemistry . The successful candidate will play ... a leading role in developing medicinal chemistry optimization strategies for key drug discovery programs. This individual will review experimental results,… more
    Frontier Medicines (11/04/25)
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  • Senior Principal Scientist , Peptide…

    Genentech (South San Francisco, CA)
    …us Genentech. **The Opportunity** We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist ) to join our innovative ... novel peptide therapeutics into clinical development. You will lead the Medicinal Chemistry efforts for a highly integrated and collaborative team, applying your… more
    Genentech (11/06/25)
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  • Senior Principal Scientist , Pre

    Pfizer (San Diego County, CA)
    **ROLE SUMMARY** This Senior Principal Scientist position will be a strong scientific and leadership role within the Early Formulation Science and Drug Delivery ... and drug delivery systems design + Integrates pharmaceutics, physical organic chemistry , biophysical chemistry , supramolecular chemistry , materials science,… more
    Pfizer (11/19/25)
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