• Sr. Downstream Processing Technician

    Actalent (St. Louis, MO)


    Description

    The candidate will help the performance of operations in support of the manufacture of Commercial and Clinical Biologics. They will follow Current Good Manufacturing Practices (cGMPs) and carrying out a variety of functions related to Downstream (purification and filtration/HPLC). These functions may include but are not limited to activities such as propagation of mammalian cell culture, conducting aseptic cell culture operations, execution of large scare production bioreactors (50L - 2000L), and conducting large scale filtration or centrifugation. Purification will be handed through large scale chromatography (column and HPLC). Manufactures buffers and simple bulk reagents per manufacturing procedures with limited supervision. Participates in process improvement projects. Key Responsibilities: • Responsible for reviewing all area documents. • Responsible for the WNS. • Assist in manufacture of controls and calibrators and complete batch records following cGMPs. • Perform in-process assays using equipment such as spectrophotometers, pH meters and clinical analyzers. • Weighing, transfer, mixing of chemicals required. • Perform product filtrations. • Clean and steam steel tanks (CIP) / (SIP). • Prepare glassware and steel tanks for sterilization in autoclave and operate autoclave. • Maintain lab equipment including pumps, pH meters, and flow meters. • Keep department lead or manager updated on all issues. • Monitor stocks of common lab supplies. • Performs other job duties as required. • Responds to Emergency notifications. • Flexible hours and on weekends.

     

    Skills

     

    Gmp, Cleanroom, aseptic technique, Cgmp, Aseptic, Laboratory, chemistry, hplc, Pharmaceutical, Pharmaceutical industry, chromatography

     

    Top Skills Details

     

    Gmp,Cleanroom,aseptic technique,Cgmp,Aseptic,Laboratory,chemistry,hplc

     

    Additional Skills & Qualifications

     

    Education: • BS Degree in STEM related field required Experience: • Required: Minimum of 2 years of work experience in manufacturing, operation, production, lab setting or related field • Preferred: Experience in a cGMP environment and 4 year STEM degree Knowledge • Knowledge of cGMP practices, aseptic techniques, or chemical concepts- preferred • Subject Matter Expert on downstream processing steps- preferred

    Experience Level

    Expert Level

    Pay and Benefits

    The pay range for this position is $27.00 - $31.00/hr.

     

    Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

     

    • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

     

    Workplace Type

     

    This is a fully onsite position in Saint Louis,MO.

     

    Application Deadline

     

    This position is anticipated to close on Jun 2, 2025.

    About Actalent

    Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

     

    The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

     

    If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.