• Research Assistant I

    Children's Hospital Boston (Boston, MA)


    80359BRJob Posting Title:Research Assistant IDepartment:CardiologyAutoReqId:80359BRStatus:Full-TimeStandard Hours per Week:40 Job Posting Category:ResearchJob Posting Description:Position Summary

     

    At Boston Children’s Hospital, success is measured in patients treated, parents comforted and teams taught. It’s in discoveries made, processes perfected, and technology advanced. In major medical breakthroughs and small acts of kindness. And in colleagues who have your back and patients who have your heart. As a teaching hospital of Harvard Medical School, our reach is global and our impact is profound. Join our acclaimed Department of Cardiology Basic Research and discover how your talents can change lives. Yours included. We are seeking a highly motivated and independent individual as a research assistant to join our cutting-edge disease modeling group.

    Key Responsibilities

    + Performing a variety of routine and specialized laboratory experimental specimen preparations and experimental procedures for the purpose of research, while under immediate supervision.

    + Assisting in the use of specialized laboratory equipment and analysis of data generated by this equipment.

    + Developing protocols and performing experiments to model cardiac diseases with induced pluripotent stem cell (iPSC) models.

    + Perform differentiation protocols in small volume stirred bioreactors for large-scale cardiomyocyte production.

    + Maintain database of iPSC lines and interface with other lab members to ensure specimen quality and data integrity.

    + Optimize protocols for differentiation into relevant cell types.

    + Perform genome editing to enhance relevance of iPSC disease models.

    + Routine molecular biology tasks including cloning and PCR.

    + Learn and develop skills in bioinformatics to assist in the analysis of genetic data including DNA sequencing, proteomics, and single-cell RNA sequencing data.

    + Collaborate closely with bioengineers to develop novel micro-physiologic systems for human disease modeling.

    + Maintaining excellent records of results and methodologies as well assisting in compiling and analyzing data.

    + This position will not require any animal handling

    Minimum Qualifications

    Education:

    + The knowledge of theories, principles, and concepts acquired through completion of a Bachelor's degree in biology, animal science, toxicology, pharmacology or a related field.

    + A Master’s degree is highly desired but not required.

    Experience:

    + Experience with mammalian cell culture is required. • Experience with stem cell culture and biology is highly desired.

    + Intermediate laboratory skills including cell culture, molecular biology, microscopy, use of basic analytical equipment is required.

    + Excellent interpersonal skills and the desire to learn new skills are a must.

     

    Boston Children’s Hospital offers competitive compensation and unmatched benefits including flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.Office/Site Location:BostonRegular, Temporary, Per Diem:Regular Remote Eligibility :Onsite Only