• Manufacturing Associate (Upstream & Downstream)

    System One (Pennington, NJ)


    Job Title: Manufacturing Associate (Upstream & Downstream)

     

    Hours / Schedule: Full-time, shift flexibility required (day, evening, overnight rotation possible, overtime available based on production needs)

     

    Type: Temp-to-Hire (potential direct opportunity for the right fit)

    SUMMARY

    Support both Upstream and Downstream manufacturing operations in a cGMP-compliant environment. This role provides hands-on experience throughout the biologics production process — from cell culture to protein purification.

    REQUIREMENTS

    + High School Diploma or Associate’s Degree with 1–5 years of relevant GMP experience

    OR

    + Bachelor’s Degree in Biotechnology, Biochemistry, Microbiology, Chemical Engineering, or related field

    + 1–5 years of GMP experience in Pharmaceuticals, Biologics, Medical Devices, Cleanroom, or Chemical Processing environments

    + Comfortable working in sterile/cleanroom settings and following strict protocols

    + Strong interest in cross-functional manufacturing roles with growth potential

    + Open to flexible hours outside of a standard 8am–5pm schedule

    + Open to Temp-to-Hire employment

    + Ability to stand for long periods and lift up to 50 lb

    + Strong attention to detail and documentation skills

    + Willingness to cross-train and support evolving production needs

    Upstream

    + Familiarity with aseptic techniques and bioreactor operation

    + Experience with cell culture, buffer / media prep

    Downstream

    + Understanding of chromatography, TFF (Tangential Flow Filtration), viral filtration

    + Hands-on experience in cleanroom/purification operations

    RESPONSIBILITIES

    Upstream Manufacturing

    + Prepare media and buffers

    + Thaw vials, expand seed trains, and operate bioreactors (fed-batch/perfusion)

    + Monitor/document cell growth and bioreactor parameters

    + Support cell harvest through clarification and filtration

    Downstream Manufacturing

    + Conduct chromatography operations (AKTA or similar systems)

    + Perform Tangential Flow Filtration (TFF) and diafiltration

    + Execute viral filtration procedures

    + Support cleanroom-based final fill operations

    General Duties

    + Adhere to cleanroom, gowning, and aseptic protocols

    + Maintain GMP-compliant documentation

    + Clean and sanitize production equipment

    + Collaborate with Quality, Engineering, and Logistics teams

    #M3

    Ref: #558-Scientific

     

    System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

     

    System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.