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Company Information

Cambrex is a leading global contract development and manufacturing organization (CDMO) that provides drug substance, drug product, and analytical services across the entire drug lifecycle. With over 40 years of experience and a growing team of over 2,200 experts servicing global clients from North America and European sites, Cambrex is a trusted partner in branded and generic markets for API and dosage form development and manufacturing.

At Cambrex, our people set us apart. We’re committed to attracting, nurturing, and retaining a passionate and talented team of valued experts in our fast-paced and growing company. We offer an exceptional benefits package including medical, dental, vision, Life, LTD, generous vacation in your first year, sick time, and retirement savings!

Known for our scientific and manufacturing excellence, as well as our strong customer focus, we offer a range of career opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world.

Job Overview

Cambrex is seeking to hire a growth-related Research Investigator & Manager position with a highly motivated individual for the Process Chemistry department. The individual in this position will lead a team of other process chemists while demonstrating expert knowledge in advanced synthetic chemistry principles and practices. The person in this role will work across departments and the site to test and advance innovative processes, hypotheses, methodologies and technology; encourages curiosity and challenges the status quo at the site level in order to foster innovation. Must display expert knowledge in process chemistry and drug substance manufacturing requirements, and substantial experience with GMP practices, CMC principals and ICH guidelines for pharmaceutical development. Deep knowledge and experience with GMP practices, documentation and execution of batch records in a GMP environment is required. The Individual in this position will design and propose new synthetic routes to drug substances and will lead process chemistry portions of customer projects. They will frequently present work internally and externally to clients or regulatory agencies.

Responsibilities

+ Leads, mentors, manages, develops and provides support to a team of 4-6 organic synthetic process chemists

+ Performs multistep organic syntheses, isolation, and purification of targeted products independently. Contribute to the strategic approach used to optimize reactions, isolations, and purifications.

+ Proficiently conducts analyses of starting materials, reaction mixtures, intermediates and products using appropriate instrumentation.

+ Works closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.

+ Routinely generates summaries and reports on completed experimental work for internal and external use. Routine presentation of experimental work for internal meetings and teleconferences with customers.

+ Works to ensure that teamwork and cooperation exists within the group at all times.

+ Conducts laboratory operations in a safe manner. Maintains familiarity with the company’s chemical hygiene plan. Exhibits safety awareness and safe work practices.

+ Follows responsible actions regarding chemical disposal. Maintains compliance with all regulations at the federal, state, and local levels.

+ Addresses routine administrative requirements in a timely fashion.

+ Demonstrates effective communication skills (both written and oral). Participates in project team meetings with customers.

+ Works closely with manufacturing and GMP operations to coordinate project-related equipment and activities. Assist in the transfer of processes to the manufacturing team.

+ Independently designs and proposes new synthetic processes to produce the drug substance.

+ Acts as process chemistry lead for customer projects. Identify critical questions to be answered and set priorities for the process chemistry team.

+ Maintains familiarity with applicable literature including organic chemistry and techniques.

+ Participates in setting strategy and timing needed for customer proposal requests.

+ Works closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.

+ Routinely generates summaries and reports on completed experimental work for internal and external use. Oral and written presentation of experimental work for internal meetings and teleconferences with customers

+ Performs other related duties as assigned.

Qualifications/Skills

+ Demonstrates leadership skills and effectively leads, mentors, develops, and manages a team of process chemists.

+ Has advanced knowledge in synthetic chemistry transformations, reaction mechanisms and retrosynthetic analysis skill.

+ Has expert knowledge in advanced synthetic chemistry principles and practices. Has expert knowledge in process chemistry and drug substance manufacturing requirements.

+ Substantial experience with GMP practices, CMC principals and ICH guidelines for pharmaceutical development. Has deep knowledge and experience with GMP practices, documentation and execution of batch records in a GMP environment.

+ Developing significant expertise with the Quality Management System including investigations and root cause analysis.

+ Has extensive knowledge of principles, concepts, and practices of other relevant disciplines.

+ Applies technical, functional, and industry knowledge to design and independently executes experiments/projects that shape the strategic direction of one or more projects.

+ Provides department and site leadership on safety practices, root cause investigations and prevention measures.

+ Recognized within department, site and externally as an expert in field.

+ Works across department and site level to test and advance innovative processes, hypotheses, methodologies and technology; encourages curiosity and challenges the status quo at the site level in order to foster innovation.

+ Identifies opportunities to lead author on scientific manuscripts and invited presenter at external scientific events. Identifies opportunities for others to lead author or co-author publishable research.

Education, Experience & Licensing Requirements

+ PhD in Organic Chemistry with 12+ years of experience in related industry, or MS in Organic Chemistry with 20+ years of experience in related industry, or BS in Organic Chemistry with 22+ years of experience in related industry.

+ Prior experience leading a team of chemists is strongly preferred.

Physical Demands: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this Job, the employee is regularly required to use hands to finger, handle, or feel; reach with hands and arms; talk or hear and smell. The employee is frequently required to sit. The employee is occasionally required to stand; walk and stoop, kneel, crouch, or crawl. The employee must regularly lift and/or move up to 10 pounds, frequently lift and/or move up to 25 pounds and occasionally lift and/or move up to 50 pounds. Specific vision abilities required.

Environment and Protective Equipment: The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this Job, the employee is occasionally exposed to moving mechanical parts and vibration. The noise level in the work environment is usually very quiet.

The hiring range in Colorado for these positions is $140,000/year - $180,000/year depending on level which is determined by experience, education, and competencies. Base pay offered may vary depending on job-related knowledge, education, skills and experience of the applicant, internal equity, and alignment with market data. This hiring range encompasses several levels. This information is provided per the Colorado Equal Pay Act. This position includes a competitive benefits package.

Cambrex is an Equal Opportunity / Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.

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