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**Sr. Downstream Processing Technician*
- Actalent (St. Louis, MO)
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Chemistry Processing Technician – Downstream Manufacturing
St. Louis, Missouri
Rotating 12-Hour Schedule | Contract-to-Hire
Join a cutting-edge biologics manufacturing team where your work directly supports life-changing therapies. We’re seeking a Downstream Processing Technician to help produce commercial and clinical biologics in a cleanroom environment, using advanced purification and filtration technologies.
What You’ll Do
+ Execute downstream processing steps including large-scale chromatography, filtration, and bioreactor operations
+ Perform in-process assays using spectrophotometers, pH meters, and clinical analyzers
+ Prepare and sterilize glassware and steel tanks using autoclaves
+ Conduct CIP/SIP (clean-in-place/steam-in-place) procedures
+ Accurately complete batch records and ensure compliance with cGMP standards
+ Monitor lab supplies and maintain equipment (pumps, pH meters, flow meters)
+ Communicate effectively with leads and managers regarding production status
+ Work flexible hours, including weekends, as needed
What You Bring
+ Bachelor’s degree in a STEM-related field
+ 2+ years of experience in manufacturing, lab operations, or production
+ Strong understanding of aseptic techniques and cGMP compliance
+ Hands-on experience with chromatography systems and bioreactors
Work Environment
+ Night shift: 6:15 PM – 6:45 AM, rotating 12-hour schedule
+ Cleanroom/aseptic suite with strict gowning protocols (full suit required)
+ Must be able to lift 25 lbs independently and stand for 80% of the shift
+ No makeup, jewelry, nail polish, or scented products allowed in production areas
Why Join Us?
+ Be part of a mission-driven team producing life-saving biologics
+ Gain experience in a regulated, high-tech manufacturing environment
+ Opportunity for long-term growth and transition to a permanent role
+ Work at a facility known for innovation, quality, and scientific excellence
Ready to make a difference in the world of biologics? Apply now and take the next step in your scientific career.
Pay and Benefits
The pay range for this position is $32.20 - $32.20/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:
• Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Saint Louis,MO.
Application Deadline
This position is anticipated to close on Oct 2, 2025.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.
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