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Senior Associate Scientist** **(Tarrytown, NY)

Regeneron Pharmaceuticals, Inc. seeks a Senior Associate Scientist (Tarrytown, NY) to develop and characterize cellular and animal models to test novel therapeutics. Collect disease-relevant tissue from animal models of neurodegenerative disease and downstream processing including biochemical analysis, tissue sectioning, immunohistochemistry, and microscopy. Design and implement cell-based assays, and other novel technologies to better understand the mechanisms of neurodegeneration. Analyze and evaluate data. Participate in research studies designed to understand the biology behind various neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis. Present data both internally and externally, and participate in discussions in collaborative, cross-functional team environment. Local telecommuting permitted up to 1 day per week.

SALARY RANGE: $79,100.00 - $129,100.00 per year

Job Requirements:

Requires a Bachelor’s degree in Biology, Molecular Biology, Neuroscience, Biotechnology or related field and 1 year of experience in the biotechnology industry. Must have experience with: Supporting the development and characterization of novel cellular and mouse models of neurological and neurodegenerative disease; Handling of neonatal and adult mice with practical understanding of mouse anatomy; Intracerebroventricular (ICV) injection of adeno-associated virus (AAV) into neonatal mouse pups; Mouse dissection including microdissection of sub-regions of CNS tissue; Processing cell and tissue samples for various biochemical analysis including Western blot analysis, automated capillary gel electrophoresis systems such as ProteinSimple Wes and PeggySue systems, ELISA, and MSD; DNA and RNA isolation and real-time quantitative PCR (qPCR) analysis; Downstream processing of mouse tissue,

encompassing sectioning, immunostaining, immunohistochemistry, and advanced microscopy techniques, including confocal imaging and high-throughput plate reader systems such as OperaPhoenix; Utilizing in vitro cell culture systems, including both transformed cell lines and human induced pluripotent stem cells (iPSCs), with particular emphasis on their cultivation and differentiation into neuronal lineages; Conducting data analysis and evaluation using software such as Halo, GraphPad Prism, Microsoft Excel and PowerPoint; and Compiling data into presentation formats, presenting work both internally and externally and actively contributing to collaborative, cross-functional team discussions.

Apply at https://careers.regeneron.com; Reference code R42994.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.