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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub** **Function:

Pharmacology

Job Category:

Scientific/Technology

All Job Posting Locations:

San Diego, California, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist, Lead Evaluation and Cellular Pharmacology to be located in San Diego, CA.

**Purpose:** The Lead Evaluation and Cellular Pharmacology team is a part of the Discovery Technologies and Molecular Pharmacology (DTMP) organization, a critical group in the larger Discovery Sciences organization. We are committed to the delivery of high-quality chemical leads and clinical compounds in the three Johnson & Johnson Innovative Medicine therapeutic areas. This position requires deep scientific expertise in multiple fields including cellular pharmacology, assay development, compound profiling, in vitro/ex vivo technologies, and imaging capabilities with an ability to work collaboratively with internal and external partners.

You will be responsible for:

+ Learn and apply state-of-the-art drug discovery approaches in a multidisciplinary team

+ Develop, troubleshoot, and validate functional cell-based, cell-free, and ex vivo assays

+ Profile compounds to enable medicinal chemistry SAR studies

+ Profile compounds in various organotypic models

+ Collaborate across multiple therapeutic teams and functional areas

+ Analyze data and present results at program team meetings

+ Attend and present data at internal meetings and external scientific conferences

Qualifications / Requirements:

**Education** : Minimum of a Bachelor's degree in cell biology, biochemistry, or related field is required. Advanced degree is preferred.

Skills/Experience:

Required:

+ A minimum of 6 years of experience is required.

+ Expertise using and creating state-of-the-art cell-based, cell-free, and ex vivo assays

+ Prior knowledge troubleshooting assays, processes, and logistics to seamlessly implement new assays across different modalities

+ Extensive experience with cell culture and associated techniques

+ Broad hands-on experience with rodent handling across a wide range of ages

+ Deep expertise with multiplex imaging & immunofluorescence methods

+ Deep understanding of cellular biology and pharmacology

+ Proficiency with standard scientific software used for data analysis (e.g. GraphPad Prism, Genedata Screener, Perkin Elmer Signals, and Spotfire)

+ Excellent written/verbal communication and oral presentation skills

+ Ability to adapt to a fast-advancing environment in an independent manner

Preferred:

+ Hands-on experience with stable cell line creation

+ Prior management experience is a plus

+ Familiarity with high-content imaging platforms (such as Opera Phenix imagers) and associated software and data analysis packages

+ Detailed understanding of small animal anatomy

+ Expertise with laboratory automation and high-throughput screening

+ Working knowledge in immunology, neuroscience, and/or oncology therapeutic areas

The anticipated pay range for this position is $105,000 to $169,050.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/ performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:

+ Vacation - up to 120 hours per calendar year

+ Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year

+ Holiday pay, including Floating Holidays - up to 13 days per calendar year

+ Work, Personal and Family Time - up to 40 hours per calendar year

For additional general information on company benefits, please go to: https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States.

Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

This job posting is anticipated to close on September 22, 2025. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is :

$105,000-$169,050

Additional Description for Pay Transparency:

Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation –120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year Holiday pay, including Floating Holidays –13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave – 10 days Volunteer Leave – 4 days Military Spouse Time-Off – 80 hours Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits