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Scientist, Pharmacokinetics
- Merck (West Point, PA)
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Job Description
This position will contribute to our Company's drug discovery and development efforts in the Drug Metabolism and Pharmacokinetics (DMPK) Group within the Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) organization at our Research & Development Division in West Point, PA. Candidate will primarily perform lab-based activities and be responsible for generating in vitro DMPK data to guide lead candidate optimization and development efforts. Candidate will have the opportunity to work closely with scientists across the network. They will leverage novel tools and emerging technology to evolve our approach. Embedded in our Company's network, this role will facilitate the seamless transfer of protocols and data across platforms to advance our scientific strategy. Successful candidate will impact projects across therapeutic areas through their passion for generating high-quality data.
The ideal candidate will exhibit strong laboratory skills, including the ability to independently execute the bioanalysis of in vitro and in vivo samples, and possess the capacity to contribute to implementing automation to streamline workflows. Candidate must have demonstrated leadership and accountability for setting standards for excellence to deliver high-quality results within established timelines, ability to work in a team environment, excellent written and verbal communication skills, and possess an innovative mindset to participate in identification of problems and opportunities to deliver solutions.
Position Qualifications** **:
Education Minimum Requirement:
Bachelor’s degree in analytical chemistry, biochemistry, biotechnology, or related science with 1-3 years of relevant laboratory experience or a master’s degree with 0-2 years of experience.
Required Experience and Skills:
+ Strong background in analytical chemistry and/or biochemistry.
+ Hands-on experience with quantitative analysis using LC-MS or other analytical techniques.
+ Handling of enzymes, tissue preparations, and biological fluids/matrices.
+ Experience maintaining laboratory notebooks and conducting data-fitting using commercially available software packages such as Excel, Graphpad Prism, TIBCO Spotfire, etc.
+ Strong interpersonal, communication, problem solving, and collaborative attributes to deliver high-quality results in a fast-paced environment.
+ Autonomy, attention to detail, critical thinking, growth mindset.
Preferred Experience and Skills:
+ Working knowledge of ADME-related assays, such as plasma protein binding, metabolic stability, reaction phenotyping, kinetic assays, enzyme inhibition and associated analytical techniques.
+ Experience with cell culture and the conduct of cell-based assays.
+ Familiarity with troubleshooting LC-MS instrumentation.
+ Experience with robotics, assay automation, and operation of liquid handlers in support of high-throughput workflows.
+ Experience working at a research-driven pharmaceutical company or contract research organization.
_As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:_
_EEOC Know Your Rights_
_EEOC GINA Supplement_
_We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively._
Learn more about your rights, including under California, Colorado and other US State Acts (https://urldefense.com/v3/\_\_https:/www.msdprivacy.com/us/en/CCPA-notice/\_\_;!!DuJIhUBmA6S-!CgtKRhjWVCipNvp-c1-eOdkBke5VAYrFu\_nO9xLpgYVUG7B9RK2-jLDMORIX8RP5gTenY6eWKbGwCnces0j8YBDCEJ3Y\_AM$)
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Required Skills:
ADME, Analytical Chemistry, Assay, Bioanalysis, Biochemistry, Biotechnology, Cell-Based Assays, Cell Cultures, Cell Culture Techniques, Data Analysis, Data Visualization, DMPK, Drug Metabolism, Enzymology, In Vitro Assays, Laboratory Documentation, Liquid Chromatography-Mass Spectrometry (LC-MS), Mammalian Cell Culture, Metabolism, Pharmacokinetics
Preferred Skills:
Automation, Robotic Liquid Handlers
Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)
Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088\_EEOC\_KnowYourRights\_10\_20.pdf)
EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
The salary range for this role is
$85,600.00 - $134,800.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
Yes
Travel Requirements:
No Travel Required
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
OEB4, OEB5, radioactive materials
Job Posting End Date:
10/24/2025
*A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.
**Requisition ID:** R369545
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