• LCMS Lead Scientist

    Actalent (Madison, WI)


    LCMS Lead Scientist

    Job Description

    As a LC-MS Lead Scientist, you will play a pivotal role in overseeing bioanalytical studies, ensuring that all methods meet regulatory and client requirements. You will not be working directly in the lab but will be responsible for reviewing data, signing off on reports, and acting as the primary scientific point of contact. Your expertise will guide the bioanalytical study work, and you will coordinate with regulators and stakeholders, both internally and externally.

    Responsibilities

    + Oversee studies and ensure all methods are prepared, validated, executed, and documented to meet regulatory and client requirements.

    + Sign off on reports and approve raw data.

    + Act as the primary scientific point of contact for studies.

    + Coach and indirectly guide a team of up to 20 members.

    + Coordinate across internal and external stakeholders, including discussions with regulators for clinical or pre-clinical studies.

    + Travel up to 10% for cross-site or client visits.

    Required Skills

    + B.S. or Masters in Life Sciences (Chemistry, Biology, Biochemistry, etc.).

    + 2-3 years of LCMS experience.

    + Experience as a Lead Scientist with 1-5 years (LS1) or 7-9 years (LS2) of experience.

    + Must have experience as a Lead Scientist/Responsible Scientist/Principle Investigator in the Bioanalytical sector (GLP or GCP regulations).

    + Full responsibility over the study, with experience in BioA CRO regulated space.

    + LBA (Ligand Binding Assay) experience, including data review/approval, protocol/sample analysis plan development, and method validation readiness.

     

    Additional Skills & Qualifications

     

    + Experience with Sciex Mass Spec and analysis software.

    + Familiarity with LIMS, Nautilus, and Analyst software.

    + Knowledge of ICH or 28BMV regulatory guidance protocols and FDA internal standards.

    Work Environment

    The role is based in a lab setting within the Bioanalytical team, consisting of approximately 100 employees, including 60 chemists. This is a hybrid position, requiring 2-3 days onsite per week, with flexibility on the days but consistency each week. The role involves indirect reporting from method development chemists, validation chemists, sample analysis, and report writing. The work is workload-based rather than project-based, with a varying number of projects depending on client needs. The team is expanding, with current plans to increase from 16 to 18 members in Madison. Travel is limited, with a maximum of 10% required for client visits or conferences.

     

    Job Type & Location

     

    This is a Permanent position based out of Madison, WI.

    Pay and Benefits

    The pay range for this position is $85000.00 - $110000.00/yr.

     

    Medical Plan* No Charge Laboratory Testing Benefit and physical therapy Dental Plan Vision Plan Flexible Spending Accounts (FSAs) Health Care FSA Dependent Care FSA Disability Plan Short Term Disability (STD) Long Term Disability (LTD) Life and Accidental Death and Dismemberment (AD&D) Insurance Plans Basic Life Optional Life Dependent Life Optional AD&D Employee Stock Purchase Plan (ESPP)

     

    Workplace Type

     

    This is a hybrid position in Madison,WI.

     

    Application Deadline

     

    This position is anticipated to close on Jan 2, 2026.

    About Actalent

    Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

     

    The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

     

    If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.