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Scientist / Associate Scientist, Antibody…
- System One (Rockville, MD)
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Job Title: Associate Scientist/Scientist – Antibody Engineering
Hours/Schedule: Monday–Friday, core hours 8:00 AM – 5:00 PM (some flexibility)
Compensation: $30-$40/hour
Type: Contract (6 months) with potential for extension
Overview
Leading biotechnology organization is seeking a Associate Scientist/Scientist, Antibody Engineering to support antibody discovery and engineering programs. This role offers hands-on involvement in the design, optimization, and evaluation of monoclonal and bispecific antibodies using modern molecular biology and immunoassay techniques. This is a high-impact opportunity to contribute directly to early-stage biologics development in a collaborative research environment.
Responsibilities
+ Design, engineer, and evaluate monoclonal and bispecific antibodies using molecular biology techniques
+ Construct and optimize multiple antibody formats to improve affinity, stability, and developability
+ Perform and analyze immunoassays, including ELISA, to assess antibody function, stability, and serum clearance
+ Evaluate antibody performance using analytical platforms such as ELISA, flow cytometry, and Octet
+ Support experimental design, data analysis, and interpretation to guide antibody optimization strategies
+ Document experimental procedures, results, and conclusions in accordance with internal standards
+ Collaborate cross-functionally with scientists to advance antibody engineering projects toward development goals
Requirements
+ Bachelor’s degree in a scientific discipline with 2-5 years of related experience OR; Master’s degree in a scientific discipline with 1-3 years of related experience
+ Strong background in molecular biology techniques, including molecular cloning, RNA isolation, mutagenesis (QuikChange), and sequencing analysis
+ Hands-on experience performing immune-binding assays such as ELISA
+ Experience using software tools for plasmid mapping and sequence analysis (e.g., SnapGene) and ELISA data analysis (e.g., SoftMax, GraphPad Prism, Excel)
+ Ability to work collaboratively in a fast-paced, research-driven environment
+ Must be legally authorized to work in the United States for any employer
Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.
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System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
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Scientist / Associate Scientist, Antibody Engineering
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