- Boston University (Boston, MA)
- …stem cells (hiPSCs) from population and isogenic lines generated by CRISPR/Cas9 genome editing and in vivo hiPSC/rodent chimera systems in comparison with ... geneticists, neuroscientists and pharmacologists in the department as well as Genome Science Institute and Center for Systems Neuroscience at Boston University.… more
- Lilly (Boston, MA)
- …Develop and optimize workflows for iPSC gene-editing using existing and novel genome editing tools, including guide RNA design, RNP delivery, clone characterization, ... flow cytometry, DNA-based assays, ddPCR, and next-generation sequencing (NGS). + Execution of genome editing of iPSC in GMP facilities to create clinical cell lines.… more
- Harvard University (Cambridge, MA)
- …in the lab who are generating novel data for comparative genomics (whole- genome sequences, RNAseq transcriptome data, Illumina, 454, PacBio), and work to aggregate ... and cleaning; + Experience with the analysis of next-generation sequence data and whole- genome sequencing and RNA -Seq; + Fluency in English written and oral… more
- Dana-Farber Cancer Institute (Boston, MA)
- …cancer genetics and cancer risk assessment tools + Some knowledge of whole genome analysis and personalized genomic medicine + Ability to tailor, translate and ... cancer genetics and cancer risk assessment tools + Some knowledge of whole genome analysis and personalized genomic medicine + Ability to tailor, translate and… more
- Boston University (Boston, MA)
- …other omics data (transcriptomics, proteomics, and metabolomics) to decipher the genome -wide molecular pathways associated with AD risk. In collaboration with our ... geneticists, neuroscientists and pharmacologists in the department as well as Genome Science Institute and Center for Systems Neuroscience at Boston University.… more
- Harvard University (Cambridge, MA)
- …known as gene transfer agents, that package random sections of the host genome for use in genetic exchange. These virus-like entities are non-infectious and cannot ... replicate themselves, but are able to transduce random sections of the genome within a population. We aim to characterize gene transfer agent diversity, regulation… more
- Massachusetts Institute of Technology (Cambridge, MA)
- …Lab, to join a research team studying how gene expression and genome architecture are coupled. The work will involve protein expression, protein purification, ... experiments to analyze how machines involved in gene expression and genome organization interact and regulate each other's activity. The successful candidate… more
- Bristol Myers Squibb (Cambridge, MA)
- …trials and other observational cohorts, including RNA-Seq, Exome and Whole Genome Sequencing, high throughput proteomics, and imaging data to validate ... pharmacodynamics effects, confirm the mechanism of action, and enable patient enrichment strategies. Conduct analysis independently to integrate and mine large-scale external datasets to further our understanding of neurodegenerative and neuropsychiatric… more
- Harvard University (Cambridge, MA)
- …a large population in Cebu, Philippines, for more than 40 years. Recently generated genome -wide methylation data will be used to explore a range of questions, with ... topical focus flexible. Duties will involve helping coordinate a weekly lab group meeting (journal readings, in progress research talks, visiting speakers), and helping affiliated PhD and undergraduate students gain access to and work with the Cebu data. The… more
- Lilly (Boston, MA)
- …at Eli Lilly! We are responsible for inventing, characterizing, and advancing novel genome therapy reagents for a myriad of clinical applications. Our team works ... cross-functionally within our organization across multiple disease areas and platforms. Our goal is to deliver on the promise of gene therapy to patients around the world. **Responsibilities:** Lilly Gene Therapy Discovery and Platform Research (GTDPR) team… more