- Merck (Cambridge, MA)
- …new medicines that save and improve lives. Core to the Data, AI, and Genome Sciences (DAGS) function is an AI/ML-first approach to improving target and biomarker ... discovery, validation and selection, and elucidating complex disease mechanisms. Your work will contribute to the advancement of our understanding of complex diseases and support the development of innovative therapeutic strategies. You will be part of a… more
- Merck (Cambridge, MA)
- **Job Description** The Complex Disease Genetics group within the Data, AI and Genome Sciences (DAGS) Department at our Company is seeking an accomplished Associate ... experience in large-scale statistical genetics and genomics analyses, including genome -wide association studies (GWAS), rare variant association analyses, post-GWAS… more
- Boston University (Boston, MA)
- …stem cells (hiPSCs) from population and isogenic lines generated by CRISPR/Cas9 genome editing and in vivo hiPSC/rodent chimera systems in comparison with ... geneticists, neuroscientists and pharmacologists in the department as well as Genome Science Institute and Center for Systems Neuroscience at Boston University.… more
- AbbVie (Cambridge, MA)
- …understand existing knowledge gaps related to adverse events + Conduct genome -wide association analyses to identify genetic variants associated with target traits. ... informatics skills for analyzing and visualizing genomic data, such as Whole Exome/ Genome Sequencing; as well as surveillance health records + Knowledge of… more
- Harvard University (Cambridge, MA)
- …the laboratory is to develop and apply innovative computational methods for genome sequencing data to enhance our understanding of disease processes including cancer ... + Algorithms for characterizing structural alterations in bulk and single cell whole- genome data + Mutational signature analysis for cancer/brain samples + Analysis… more
- Massachusetts Institute of Technology (Cambridge, MA)
- …Lab, to join a research team studying how gene expression and genome architecture are coupled. The work will involve protein expression, protein purification, ... experiments to analyze how machines involved in gene expression and genome organization interact and regulate each other's activity. The successful candidate… more
- Lilly (Boston, MA)
- …Develop and optimize workflows for iPSC gene-editing using existing and novel genome editing tools, including guide RNA design, RNP delivery, clone characterization, ... flow cytometry, DNA-based assays, ddPCR, and next-generation sequencing (NGS). + Execution of genome editing of iPSC in GMP facilities to create clinical cell lines.… more
- Harvard University (Cambridge, MA)
- …in the lab who are generating novel data for comparative genomics (whole- genome sequences, RNAseq transcriptome data, Illumina, 454, PacBio), and work to aggregate ... and cleaning; + Experience with the analysis of next-generation sequence data and whole- genome sequencing and RNA -Seq; + Fluency in English written and oral… more
- Dana-Farber Cancer Institute (Boston, MA)
- …cancer genetics and cancer risk assessment tools + Some knowledge of whole genome analysis and personalized genomic medicine + Ability to tailor, translate and ... cancer genetics and cancer risk assessment tools + Some knowledge of whole genome analysis and personalized genomic medicine + Ability to tailor, translate and… more
- Boston University (Boston, MA)
- …other omics data (transcriptomics, proteomics, and metabolomics) to decipher the genome -wide molecular pathways associated with AD risk. In collaboration with our ... geneticists, neuroscientists and pharmacologists in the department as well as Genome Science Institute and Center for Systems Neuroscience at Boston University.… more