- AbbVie (South San Francisco, CA)
- …candidate will establish innovative translational modeling approaches, such as mechanistic PK /PD or systems modeling, across disease and therapeutic areas, as well ... clinical pharmacology, and other stakeholders, to develop and execute QTAS and PK /PD strategies necessary to facilitate the advancement of our pipeline. Key… more
- Otsuka America Pharmaceutical Inc. (Sacramento, CA)
- …study execution, reporting and interpretation of data. + **Conduct** **Physiologically-Based Pharmacokinetic (PBPK) modeling** **,** **population PK , PK /PD ... you will support all **pharmacometrics** activities related to pre-IND, IND, phase1-3, PK , PK /PD and regulatory submissions. You will conduct analysis, execution… more
- Amgen (South San Francisco, CA)
- …You will characterize the absorption, distribution, metabolism, excretion (ADME) and pharmacokinetic ( PK ) properties of SM therapeutic drug candidates to ... skills such as in vitro ADME, in vivo ADME, biotransformation, PK /PD, or physiologically-based pharmacokinetic modeling (PBPK) to impact project progression… more
- BeOne Medicines (Emeryville, CA)
- …The Director of Biostatistics will provide strategic statistical leadership for pharmacokinetic ( PK ) and pharmacodynamic (PD) studies across all phases ... analysis, and timely support for global regulatory submissions. Deep expertise in PK modeling, including non-compartmental and population PK analysis, and… more
- Gilead Sciences, Inc. (Foster City, CA)
- …of this Biologics DMPK Director position is to serve as an expert in the PK and PK /PD of biologics, representing the DMPK department by providing strategic and ... discovery and development as a subject matter expert for DMPK Biologics, providing PK or PK /PD expertise to the design of nonclinical PK , toxicology, or… more
- Children's Hospital Los Angeles (Los Angeles, CA)
- …be responsible for supporting development and maintenance of population pharmacokinetic /dynamic analysis, simulation and dosing programs. The CHLA INSPIRE ... hollow fiber infection model (HFIM) to mimic human pharmacokinetics and pharmacodynamics ( PK -PD) in vitro to improve dosing strategies and select ideal combination… more
- AbbVie (South San Francisco, CA)
- …projects and Clinical Pharmacology and Pharmacometrics (CPPM) goals. Generate new PK /PD proposals and lead those efforts. Investigate, identify, develop, and ... optimize new methods and techniques in PK /PD field. Act as a lead PK scientist in his/her area of expertise and critically evaluate relevant Clinical… more
- AbbVie (South San Francisco, CA)
- …for effective performance of the teams. Responsibilities + Leads Clinical Pharmacology/ PK /PD activities and multiple major projects. Assists R&D senior management in ... sponsorship. + Contribute to development of departmental goals. Influences strategic PK /PD decisions for the department. + Performs functions and responsibilities… more
- Merck (South San Francisco, CA)
- …companies. **Responsibilities:** + Develop model-based strategies (translational PK /PD strategies, mechanistic model, POPPK/PD, clinical trial simulations, ... engineering, or a related field. + Experience in performing population PK /PKPD analyses using standard pharmacometrics software (eg NONMEM, Monolix, Phoenix, etc.)… more
- Kelly Services (Thousand Oaks, CA)
- …levels in plasma, brain, and other tissues. + Design and interpret Pharmacokinetic /Pharmacodynamic ( PK /PD) studies to evaluate drug delivery, efficacy, and ... 8-10+ years of industry experience in bioanalytics, biodistribution, and PK /PD studies, ideally with large molecules (antibodies, oligonucleotides, peptides).… more