• Principal Scientist, Computational

    Frontier Medicines (Boston, MA)
    …with short communication lines across functions and departments, and regular interactions with senior leaders. As the senior computational chemist, there is ... Medicines is seeking a highly motivated individual to fill the position of Principal Scientist, Computational Chemistry. The successful candidate will play a… more
    Frontier Medicines (11/04/25)
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  • Senior Principal Scientist

    Bristol Myers Squibb (Cambridge, MA)
    …lives. Read more: careers.bms.com/working-with-us . A position is available for an Sr Principal / Principal Scientist in Discovery Toxicology (DT) within ... and progression into development. The candidate will have demonstrated experience leveraging computational toxicology tools and big data analytics to generate… more
    Bristol Myers Squibb (11/16/25)
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  • Senior Principal Scientist…

    Schrodinger (Cambridge, MA)
    We're looking to hire a ** Senior Principal Scientist** or **Director of Medicinal Chemistry** to join us in our mission to discover and develop drugs that ... improve human health through the use of breakthrough computational methods. Our drug discovery and early clinical development team includes a cross-functional group… more
    Schrodinger (10/11/25)
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  • Senior Principal Research Engineer

    Autodesk (Boston, MA)
    **Job Requisition ID #** 25WD92933 **Position Overview** As a ** Senior Principal Research Engineer** on the **AEC Solutions** team, you will join a group of ... across multiple representations, including 2D/ _3D_ _geometry_ + Experience with computational _geometry_ and geometric data methods + Familiarity with… more
    Autodesk (11/06/25)
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  • Principal Advisor - Batteries

    Pacific Northwest National Laboratory (Boston, MA)
    …levels. Reporting to the Director of the Energy Processes and Materials Division, the Principal Advisor will serve as PNNL's senior leader for battery R&D. In ... directorates include National Security, Earth and Biological Sciences, Physical and Computational Sciences, and Energy and Environment. In addition, we have an… more
    Pacific Northwest National Laboratory (10/17/25)
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  • Principal Applied Scientist, AGI…

    Amazon (Boston, MA)
    Description As a Principal Scientist within the Artificial General Intelligence (AGI) organization, you are a trusted part of the technical leadership. You bring ... automated curricula, and science of scaling. Lead cross‑org initiatives. Mentor senior scientists and engineers. Own delivery under strict timelines. Ship production… more
    Amazon (10/30/25)
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  • Principal UI/UX Designer

    Cadence Design Systems, Inc. (Boston, MA)
    …first-in-class cloud-native platform for molecular design, cheminformatics and data management ("Orion"). Everyone, from top twenty pharmaceutical companies ... You will partner with product, UI engineering, drug-discovery science, marketing and senior leadership to oversee the user experience of therapeutic design. In your… more
    Cadence Design Systems, Inc. (10/16/25)
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  • Senior Staff Engineer, Modeling

    Takeda Pharmaceuticals (Boston, MA)
    …with methods for achieving and controlling high standards of purity and quality. The Senior Staff Engineer - Process Modeling will join a dynamic and innovative team ... Process Engineering & Technology Group. Join Takeda as a Senior Staff Engineer - Modeling where you will have...models for studying unit operations using both first-principle and data -based models. The role includes the application of process… more
    Takeda Pharmaceuticals (08/29/25)
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  • Senior Research Scientist - AI and ML…

    Pacific Northwest National Laboratory (Boston, MA)
    …directorates include National Security, Earth and Biological Sciences, Physical and Computational Sciences, and Energy and Environment. In addition, we have an ... a strong technical foundation in power and energy systems and advanced data analytics to drive innovation, transform markets, and shape energy policy.… more
    Pacific Northwest National Laboratory (11/01/25)
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