- Takeda Pharmaceuticals (Boston, MA)
- …knowledge. **Job Description** **_Objective / Purpose:_** The Director, Small Molecule In Vitro Pharmacology (IVP) plays a pivotal role in small molecule drug ... pipeline and scientific objectives. **_Accountabilities_** + Lead the in vitro pharmacology efforts for proprietary, differentiated small molecule asset generation… more
- Alloy Therapeutics (Waltham, MA)
- …who have less flexibility. We are all one team! The Team Alloy's In Vitro Pharmacology team collaborates with drug discovery partners to conduct in vitro ... We are seeking a highly motivated Scientist for in vitro screening and pre-clinical development to join our dynamic...this role, you will support the execution of in vitro functional cell-based assays to evaluate the potency, mechanism… more
- Alloy Therapeutics (Waltham, MA)
- …who have less flexibility. We are all one team! The Team The In Vitro Discovery team is a collaborative group driving antibody discovery and optimization using ... contribute to antibody discovery and optimization campaigns using state-of-the-art in vitro platforms. This role requires a highly motivated and detail-oriented… more
- AbbVie (Worcester, MA)
- …& for core therapeutics areas. + Design & execute in vitro display technologies for lead antibody identification/optimization to generate stage-gate appropriate ... in vitro / cellular / in vivo data packages supporting...must have 5 years: (i) performing experiments utilizing in vitro antibody discovery display technologies including phage, yeast; (ii)… more
- AbbVie (Worcester, MA)
- …core therapeutic areas. Key responsibilities include designing and executing in vitro display technologies for lead antibody identification and optimization. The ... or 12-14+ (BS) years of experience. + Hands-on experience with in vitro antibody discovery display technologies (eg, phage, yeast, mammalian). + Extensive experience… more
- Sanofi Group (Cambridge, MA)
- …ability to integrate into multi-disciplinary project teams, contributing technical in vitro and in vivo skills. Responsibilities will include in vitro ... and perform reporter assays as well as other in vitro assays including, but not limited to ELISA, MSD,...cell biology + Experience in aseptic technique for in vitro cell culture. + Experience in isolating and/or culturing… more
- Merck (Boston, MA)
- …novel bioluminescence (Nano-Luc) substrates. The successful candidate will contribute to in vitro and in vivo assay development, substrate testing, and data analysis ... lines expressing Nano-Luc/Firefly-Luc using viral transduction + Perform in vitro bioluminescence assays using Nano-Luc/Firefly-Luc expressing cell lines to evaluate… more
- AbbVie (Worcester, MA)
- …Purpose This role will be responsible for evaluating immunogenic risk potential in vitro of candidate therapeutic large molecules and develop novel in vitro ... development of preclinical molecules. Key Responsibilities + Execution of in vitro immunogenicity and immunosafety platform for risk assessment. + Implement… more
- System One (Boston, MA)
- …such as Incucyte and Xcelligence will be a plus + Proficient in developing in vitro assays, including work with human cell lines, PBMCs, and whole blood assays. + ... novel allogeneic cell therapies by developing immune cell-based assays, executing in vitro experiments, and assessing immune response to different gene edited cells.… more
- Pfizer (Cambridge, MA)
- …biopharmaceutics with a focus to improve predictive capabilities by linking in vitro drug and drug product performance attributes to in vivo performance attributes ... efflux) transport phenomena, design, interpretation, and use of in vitro experiments, or in vivo/in vitro drug...of in vitro experiments, or in vivo/in vitro drug metabolism studies, and interpretation of pre-clinical exposure… more