- Merck (Cambridge, MA)
- …Research Organizations (CRO). The ideal candidate will be an experienced in vitro biology bench scientist and team player with experience supporting collaborations ... include but are not limited to the following:** + Relying on in vitro biology lab bench experience, partner with pharmacologists from QB and scientists from… more
- Takeda Pharmaceuticals (Boston, MA)
- …therapies to patients worldwide. **_Objective / Purpose:_** The Director, High-Throughput In Vitro ADME is a senior scientific and operational leader responsible for ... building and directing Takeda's high-throughput in vitro ADME capabilities in support of small- and large-molecule...and execute the multi-year strategic roadmap for high-throughput in vitro ADME at Takeda, aligned with the broader vision… more
- Takeda Pharmaceuticals (Boston, MA)
- …therapeutic areas of interest: Oncology, Gastroenterology and Neuroscience. Biologics In Vitro Pharmacology (BIVP) role is to identify the therapeutics candidates ... Expertise** + Experienced in the design, development and implementation of in vitro /ex vivo cell-based functional assays to study target-specific drug effects. +… more
- Sanofi Group (Cambridge, MA)
- …RNA degradation mechanisms as well as perform state-of-the-art computational and in vitro techniques associated to prediction, analysis and validation of those RNA ... syndrome or SYNGAP1 syndrome. The candidate will have hands-on experience in vitro and in vivo skills to support phenotypical assessment of neurodevelopmental… more
- Takeda Pharmaceuticals (Boston, MA)
- …teams and external partners. Design, execute, and interpret functional in vitro , and ex vivo assays to understand the therapeutic mechanism-of-action and ... evaluation of novel engagers for Vd1 T-cells in in vitro and ex vivo model systems. Contribute to development...Vd1 gamma delta T cells; Design and execute in vitro /ex vivo assays of Vd1 cell function, including cytotoxicity,… more
- Sanofi Group (Cambridge, MA)
- …to achieve go/no-go decisions + Design, conduct, and direct in vitro mechanism-of-action, proof-of-concept, and biomarker studies to validate targets and evaluate ... experience, including work with primary cells, iPSC-derived cells, or 3D in vitro models + Comprehensive experience with a broad range of molecular, cellular,… more
- Bristol Myers Squibb (Cambridge, MA)
- …translational and early clinical development organization which exploits state-of-the-art in vitro , in vivo and ex-vivo models of Cancer biology and Immuno-oncology ... of action and resistance . + Have familiarity with commonly utilized in vitro oncology and cancer immunology models and assays. + Experience performing laboratory… more
- System One (MA)
- …culture techniques, including primary immune cell handling, isolation, and in vitro stimulation. + Experience maintaining cell lines and working with large-scale ... cell screening approaches such as CRISPRi, CRISPRa, or other in vitro gene-editing methods. + Experience generating or working with single-cell transcriptomics… more
- Actalent (Cambridge, MA)
- …immune cells handling and isolation, maintenance of cell lines and in vitro stimulation of primary immune cells, experience with standard molecular biology ... of immune cells using CRISPRi, CRISPRa, and other methods of in vitro gene editing. PHYSICAL POSITION REQUIREMENTS: * Typical bench work, including sitting,… more
- Merck (Boston, MA)
- …of the successful candidate will be to develop and characterize novel in vitro and ex vivo translational pharmacology assays to support autoimmune and cancer ... Enzyme Linked Immunosorbent Assay (ELISA), Flow Cytometry, Innovation, In Vitro Assays, Laboratory Safety, Luminex Assays, Mammalian Cell Culture, Molecular… more